Project Protect – Antibiotics Over Time

Project Protect – Antibiotics Over Time

In 1928 Dr. Fleming Discovered penicillin
when his petri dish covered with bacteria began to die. Approximately 10 years later Dr. Florey and
Dr. Chain Further investigated this subject by looking into Dr. Fleming’s cases. This case was further studied by using mice
as test subjects where 50 percent of them received penicillin and the other 50 percent
did not. Those that received penicillin ended up living
while those that did not receive penicillin ended up dying. Antibiotics such as that discovered
Fleming have specific attack sites to eliminate microbes. In order to kill these invaders, antibiotics
inhibit protein synthesis, inhibit DNA synthesis, and as with penicillin inhibit cell wall synthesis. However, microorganisms have found ways to
combat these mechanisms of action. These resistance methods include changes in
antibiotic permeability, alteration of target molecules, enzymatic degradation of antibiotics
and efflux of anti-microbials from the cytosol. Through evolution, resistance is increasing
at an alarming rate. A rate in which we are failing to keep up
with. The overuse of antibiotics is one of the major
causes of increasing resistance. Antibiotics are often over-prescribed by health
workers, veterinarians, and overused by the public. Since the 1940’s, we have been giving out
antibiotics at an alarming rate and we are just realizing the effects that are taking
place. Antibiotics are often prescribed as general
treatment, even in cases when patients show no symptoms. For cases such as this, antibiotics aren’t
necessary. Antibiotics are also given to animals and
crops that produce food. The vast majority is used on healthy animals
to promote growth or prevent disease in crowded or unsanitary conditions. Therefore, antibiotics are used in copious
amounts on animals that are healthy and don’t require treatment. It is crucial to develop different strategies
that would prevent overuse of antibiotics. One suggestion is to preserve the lifespan
of antibiotics by rotating the use of different antibiotics prescribed to humans or even used
on animals. Antibiotics therapy can remain effective if
rotation of these drugs is kept successful throughout. Another strategy would encourage the use of
vaccinations. Vaccinations are an efficient way to fight
common colds and infection, so avoid the use of antibiotic treatment. Lastly, it is important to always take the
medications as prescribed. If you do not finish prescriptions as indicated
then you are only making the bacteria stronger against antibiotics. That’s why it is always important to always
listen to your doctor.


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