2017 Research Highlights from Johns Hopkins Medicine

2017 Research Highlights from Johns Hopkins Medicine


Let’s look back at ten scientific
discoveries this year at Johns Hopkins. In research heralded as a successful
example of personalized medicine, people with cancer who have flaws in certain genes that help repair DNA responded to a new drug that targets the immune system. This finding led the FDA to expand use
of the drug to these patients. Experiments in mice demonstrate that alcohol may make things worse when it comes to ridding the mind of fearful experiences, like those associated with post-traumatic stress disorder. In a small study, Johns Hopkins researchers report that most people suffering cancer related anxiety or depression found considerable relief for
up to six months from a single large dose of psilocybin, the active compound
in hallucinogenic magic mushrooms. In mice and human cells,
Johns Hopkins scientists found that selectively removing old or senescence
cells from joints could stop and even reverse the progression of
osteoarthritis. Johns Hopkins researchers have studied cells in mice, flies, and humans to find the traffic jams of materials going in and out of the cell’s
nucleus may cause brain damage in Huntington’s disease, an inherited adult
neurodegenerative disorder. When it comes to emergency stroke care, Johns Hopkins researchers tested flying a stroke specialist by helicopter to a nearby
stroke patient. The result? Cheaper and faster care. Working with six Colombian
hospitals, Johns Hopkins researchers have found biological evidence linking Zika
virus infection with Guillain-Barré syndrome, a rare but potentially
paralyzing disorder of the nervous system. An experimental gene-therapy aimed at preserving the vision of people with wet
aged macular degeneration or AMD is proven safe in a small clinical trial. Johns Hopkins and other international researchers have completed the design
phase for a fully synthetic yeast genome and then another pivotal step in gene
sequencing, a team of Johns Hopkins researchers assembled the most complete genome sequence to date of the most common type of wheat, used to make bread. Finally, Johns Hopkins scientists have explored why we need sleep. They found that sleep re-calibrates brain cells responsible for both learning and memory. Stay tuned to a new year of research and discoveries by going to Hopkins Medicine.org/research. Subscribe to Fundamentals, our monthly
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